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Hyperphosphatemia is characteristic of FGFR inhibitors and may be difficult to manage for some patients

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Secondly, it is worth noticing that only 1625 patients were involved in the 17 RCTs, which justifies the performance of more large-scale RCTs for evaluating the impact of L-C treatment on CHF patients

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Arg194 is modified to Gln in the slaty mutant and this single amino acid change is solely responsible for the drastic reduction in the enzyme activity of the enzyme (Jackson et al., 1992