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Moreover, it is employed in the preservation of protein-dithiols by the protein disulfide reductase (glutathione) (EC 1.8.4.2), an enzyme that catalyzes the chemical reaction: This enzyme acts on different substrates, such as insulin, which is inactivated by cleavage of the disulfide bridge, or on protein disulfide, in which the reduction to protein-dithiol restores the catalytic activity, protecting the cell from oxidant stress

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2 (download XLSX Numerical data for titration experiments Source Data Fig

[DOI] [PMC free article] [PubMed] [Google Scholar] 68.Bosomworth HJ, Ford D, Valentine RA

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