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Interpretation of Preclinical Models: Animal and cell models provide valuable mechanistic insights, but: Rodent biology does not always predict human responses

Balanced Inflammation Control Rather than indiscriminately suppressing all inflammation, which can actually interfere with healing, therapeutic peptides selectively regulate inflammatory pathways

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The treatment group showed significant reductions in body weight (approximately 5% loss) and white adipose tissue mass (35% reduction) compared to control animals, despite no changes in food intake