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10.1007/s12264-018-0269-8 22 WangY.LomakinA.KanaiS.AlexR.BelliS.DonzelliM.et al (2016)

Research Use Only Notice Designated as research-use-only material
It is under investigation in preclinical and clinical studies on overweight, obesity, and metabolic disorders, where researchers have examined its effects on body weight and energy intake, including when combined with GLP 1 receptor agonists such as semaglutide, but it is not an approved therapy

Cizza G, Skarulis M, Mignot E

These symptoms happen due to nerve damage caused by the deficiency
