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We have recently shown that suppression of LIP expression results in a metabolic shift towards more fatty acid -oxidation (FAO) in cell culture experiments and in a mouse model that is deficient in LIP expression (C/EBP uORF mice) 12

however, the latter is still just a hypothesis (Seitz et al., in vitro (Yan et al., 2+ into the cell, which interacts with calmodulin and induces an increase in the activity of neuronal nitric oxide synthase (nNOS)

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J Biol Chem 267(6):41614165 Enerback S, Semb H, Bengtsson-Olivecrona G, Carlsson P, Hermansson ML, Olivecrona T, Bjursell G (1987) Molecular cloning and sequence analysis of cDNA encoding lipoprotein lipase of guinea pig
