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Instead, it still gets exposed to mycotoxins, further worsening the condition

Nedd4 can be induced upon erastin treatment in melanoma cells, and Nedd4 leads to VDAC 2/3 ubiquitination and mitochondrial pore degradation [50]

ROS is a broad term that includes oxygen radical and non-radical compounds, such as H2O2, hydroxyl radicals, lipid radicals and (phospho)lipid hydroperoxides (82)

Note, hepatic artery perfusion could be essential for recovery from hepatic venous outflow obstruction in rats, pointed out when usually occurring after 70% hepatectomy and right median hepatic vein ligation, in which the role of hepatic artery inflow is of particular importance, in the condition likely even more severe than the obstruction of the hepatic veins by ligation of the upper part of inferior caval vein[51]

These medical disorders are probably caused by the extensive expression of angiotensin-converting enzyme 2 (ACE2) receptor (i.e., facilitator of SARS-CoV-2 entering cells) and many dysfunctional biological processes (such as chronic inflammation, endocrine disorders, immune disorders, tissue damage, tissue hypoxia, dysbacteriosis, coagulation and endothelial abnormalities, and neurological signal dysfunction) (Szabo et al., 2023