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Description
10.1124/jpet.102.039735 281 XiZ

Concluding Remarks The large number of distinct regulatory mechanisms implicated suggests that multiple, overlapping and, in some instances, possibly redundant mechanisms contribute to tolerance to opioids
People with Pernicious Anaemia may present with symptoms of associated disorders, for example, thyroid disorders, vitiligo, diabetes, or Addisons disease

Receptor localization returns to normal only several weeks after the end of drug exposure

Additionally, such an effect means that there is a consistent matching of pressure disturbances, i.e., intraocular (intraocular pressure) and extra-ocular (intracranial, portal, caval hypertension, and aortal hypotension)
