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Additionally, AOD9604 does not exert diabetogenic (leading to development of diabetes) side effects
At standard dosing ranges of 200500 mcg daily, it supports lipolysis, fat oxidation, and reduced fat storage, while avoiding increases in IGF-1 or negative impacts on glucose metabolism
Thus, trigonelline might be an interesting therapeutic strategy as an NAD + modulator to explore in sarcopenia and possibly other chronic conditions
