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In glaucoma, reactive microglial cells initially phagocytize the debris of damaged or dead RGCs, contributing to the maintenance of a toxin-free microenvironment, and also release neurotrophic factors such as BDNF or CNTF, providing neuroprotection and promoting tissue neuroregeneration (Silverman and Wong, 2018

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doi: 10.1002/adhm.201700831
Diabetes Care , 47 (2024)
