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The precise molecular mechanisms remain to be further explored in future researches, and the animal experimental model is also needed to be improved to clarify the changes in tendon biomechanics

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Subsequent studies have confirmed that atRAL can trigger ferroptosis in 661W neuronal cell cultures by hindering system Xc , increasing Fe 2+ levels, and amplifying mitochondrial ROS production

Neurotrophic factors Neurotrophic factors, including glial cell line-derived neurotrophic factor (GDNF), have been shown to have positive effects on dopaminergic neurons in pre-clinical models of Parkinson's disease

[DOI] [PMC free article] [PubMed] [Google Scholar] 59.Laencina L, Dubois V, Le Moigne V, Viljoen A, Majlessi L, Pritchard J, Bernut A, Piel L, Roux A-L, Gaillard J-L, Lombard B, Loew D, Rubin EJ, Brosch R, Kremer L, Herrmann J-L, Girard-Misguich F