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Because early detection can reverse symptoms before permanent nerve damage occurs, a clinical workup is warranted if a patient exhibits any of the signs below

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As key mitochondrial GTPases, Mfn1 and Mfn2 mediate the fusion of outer mitochondrial membranes (Tokuyama and Yanagi, 2023)

34 Moreover, histamine inhibits neutrophil chemotaxis by acting on its type 2 receptor (H 2 ) hence an effect mimicked by the H 2 agonist impromidine, but not by the H 1 agonist betahistine