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Deficiency or malfunction of catalase is postulated to be related to the pathogenesis of many age-associated degenerative diseases like diabetes mellitus, hypertension, anemia, vitiligo, Alzheimer's disease, Parkinson's disease, bipolar disorder, cancer, and schizophrenia

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A study involved pretreating poly(I:C)-injected mice mothers with anti-IL-17a-monoclonal antibodies to induce MIA via cytokine release, was reported to partially alleviate abnormal social interaction difficulties and repetitive behaviors and preserve normal cortical development in MIA offspring [71]