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Indeed, since pro-tumoral macrophages require iron to differentiate, iron chelation may sensitize tumors to immune-based therapies

Acid reflux or heartburn worsens for some people due to delayed gastric emptying

Global statistics show that ~49% of malignant brain tumors are glioblastomas and 30% are diffuse infiltrating low-grade gliomas (1)

By reducing circulating estrogen concentrations, these inhibitors effectively decrease the stimulation of melanocytes, which are known to be highly responsive to estrogenic activity

Zhang T, Gu F, Lin W, Shao H, Jiang A, Guan X (2025) Boosting cancer immunotherapy: drug delivery systems leveraging ferroptosis and immune checkpoint blockade