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[25] With increasing numbers of proliferating stem cells in the germ line, NAD+ repletion greatly prolonged lifespan and postponed the onset of accelerated aging in animal models

Rapidly increasing lipid peroxides may inhibit pyroptosis, while chronic accumulation, such as in GPX4 deficiency, triggers inflammasome activation and cell death

317 Researchers have found that Fer-1 binds to 15LOX/phosphatidylethanolamine binding protein-1 (PEBP1) complex, suppressing the generation of peroxidized eicosatetraenoyl-phosphatidylethanolamine (ETE-PE) and protecting against ferroptosis

aTF-based CFE biosensors have primarily been developed for the purpose of field-deployable small molecule detection, such as for environmental contaminants (e.g., pesticides 142,661 and heavy metals 262,630,639,662 ) and human health markers (e.g., drugs 629,638 and metabolites 638 )

References Abdalla E.K., Caty M.G., Guice K.S., Hinshaw D.B., Oldham K.T