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The approval of injectable semaglutide for adolescents aged 12 and older in 2022 established a precedent for GLP-1-based weight management in younger patients, and an oral option could substantially change the treatment calculus for this population

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*Correspondence: Jian Zhou, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

As calcium levels can be viewed as the circuit output, their feedback inhibition forms an integral feedback that underlies exact adaptation, in analogy to the exact adaptation observed in the E