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These challenges, along with potential strategies to overcome them, are summarized in Figure 2, which highlights the translational barriers of NRF2-targeted therapies and outlines proposed solutions such as patient-derived models, selective inhibitors, and biomarker development
Li T, Yu P, Chen Y, Sun B, Dong P, Zhu T, et al
However, the recent genome-wide association studies (GWASs) with large groups of patients and healthy donors failed to prove the mentioned associations with oxidative stress-related genetic polymorphisms [8891]
KPV supports immune balance and inflammatory control
