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Instead, inoculation with BacA induced a greater upregulation of proinflammatory cytokines than IcL and wild-type in both models and a greater expansion of cytotoxic and memory T-cells than uninfected control in calves

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In Vivo Study Taking into consideration the results from the series of screening studies above, Compound 1.70 was selected for in vivo study as it showed retention in activity with all of the key enzymes (GST, GPx, and GR) while also displaying improved stability, as opposed to the other compounds that had lost activity with one or more key enzymes

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3.2 Suppression of EMT process EMT is a reversible cellular reprogramming process enabling epithelial cells to acquire migratory mesenchymal traits