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The phagocyte-produced ROS can reach T cells and cause oxidative stress (Fig
doi: 10.3945/ajcn.110.004853
Likewise, NAD depletion contributes to oxidative stress, as NAD enhances antioxidant capacity by increasing glutathione levels and antioxidant enzyme activity (209)
Since L-citrulline can be readily converted to L-arginine, it provides a recycling pathway for the conversion of L-citrulline to NO via L-arginine [14, 17]
