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doi:10.1159/000205051

Although Necrostatin-1 has demonstrated promising effects in experimental research, its pharmacokinetic properties and long-term safety require further investigation for clinical application

In addition, the lack of an endogenous equivalent of the HaloTag protein in mammalian cells minimizes the chance of detecting false positives or nonspecific interactions

Advanced oxidation protein products induce mesangial cell perturbation through PKC-dependent activation of NADPH oxidase
