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34 We demonstrated that tonic GABA currents, primarily driven by astrocytic GABA, 17 were significantly higher in PTSD-like mice compared to controls when measured following the administration of a GABAA receptor antagonist, bicuculline (50 M) (Fig

indicated that the combination treatment between Tacrolimus (Tac) and Lactobacillus acidophilus ( L

Pathogenesis of Alzheimer's Disease The pathogenesis of AD is multifactorial, involving the interplay of genetic, environmental, amyloidbeta (A) plaque deposition, tau hyperphosphorylation, oxidative stress, neuroinflammation, and synaptic dysfunction

146 In the nucleus, it transcriptionally represses PINK1 , a key mitophagy initiator, leading to reduced mitochondrial turnover

Jain L, Sharma BC, Srivastava S, Puri SK, Sharma P, Sarin S