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Using this invasive technique, intra-arterial infusion of lipoic acid was found to improve endothelium-dependent vasodilation in 39 subjects with type 2 diabetes but not in 11 healthy controls (62)

Menon, D

doi: 10.1523/JNEUROSCI.2461-07.2007

Its mechanism of action is due to the fact that it assists with maintenance of intestinal mucosal integrity, modulation of inflammatory response, nucleotide biosynthesis, energy metabolism, and stimulation of immunity (Perna et al., 2018)