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PMID: 39640291 Eur J Pharmacol GLP-1RA partially alleviates obesity-induced reproductive dysfunction driven by the interplay mechanisms of inflammation and metabolic dysregulation via the SIRT-associated pathway

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Kakizawa S, Yamada K, Iino M, Watanabe M, Kano M

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Additionally, the overexpression of Hsp70 in mice has been shown to reduce the amount of misfolded and aggregated -synuclein species, suggesting a protection of this chaperone against -synuclein-dependent toxicity [122]

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Because typical early atherosclerotic lesion formation observed in hyperhomocysteinemic animals can be prevented by an antiplatelet therapy with dipyridamole, the authors concluded that platelet-mediated proliferation of smooth muscle cells is a potential cellular mechanism involved in the atherogenicity of hyperhomocysteinemia

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