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Strittmatter WJ, Saunders AM, Schmechel D, Pericak-Vance M, Enghild J, Salvesen GS, et al

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2 ) decreased neurotransmitter vesicle and mitochondrial anterograde and retrograde transport along microtubules that would lead to decreased neurotransmission and to diminished levels of needed ATP to maintain synaptic membrane ion gradients (-tubulin, neurofilament protein medium)

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