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Vet J 2013;198:551-559

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NRF2 activation plays a key role in cellular repair during sleep by upregulating antioxidant enzymes (SOD, catalase, HO-1), reducing oxidative damage, and promoting mitochondrial biogenesis, which are critical for neuronal recovery and energy homeostasis

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The TNF- concentration of aged mice consuming the control diet in the study increased with age, whereas BC intake had no effect on TNF- concentration in young mice, which may be due to the fact that the anti-inflammatory effect of BC is more pronounced in the pro-inflammatory state

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Through suppression of NF-B and STAT3 signaling nodes, resveratrol attenuates protumorigenic inflammation and reprograms immune cell function [22, 23]

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Ohrmann, P

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