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ASK-1 inhibitors have been shown to improve inflammation and fibrosis in animal models of MASH, but Selonsertib's phase III trial does not meet its primary endpoint (265)

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Crit Care Med (2005) 33(3):56473.10.1097/01.CCM.0000155991.88802.4D 63 XiangZSnouwaertJNKovarovaMNguyenMRepenningPWLatourAMet alMice lacking three Loci encoding 14 glutathione transferase genes: a novel tool for assigning function to the GSTP, GSTM, and GSTT families

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10.1016/j.jinorgbio.2014.09.013 87 JanoP.SpinelloA.MagistratoA

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Cellular folding determinants and conformational plasticity of native C-reactive protein

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