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ASK-1 inhibitors have been shown to improve inflammation and fibrosis in animal models of MASH, but Selonsertib's phase III trial does not meet its primary endpoint (265)
Crit Care Med (2005) 33(3):56473.10.1097/01.CCM.0000155991.88802.4D 63 XiangZSnouwaertJNKovarovaMNguyenMRepenningPWLatourAMet alMice lacking three Loci encoding 14 glutathione transferase genes: a novel tool for assigning function to the GSTP, GSTM, and GSTT families

10.1016/j.jinorgbio.2014.09.013 87 JanoP.SpinelloA.MagistratoA

Cellular folding determinants and conformational plasticity of native C-reactive protein

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