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DEHP mediates drug resistance by directly targeting AhR in human breast cancer

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Compared to the controls, PD patients had higher contents of 3-methoxytyramine, N-acetyl-L-tyrosine, orotate, and urine vanillic acid xanthine, but lower levels of imidazolylactate 3,3-dimethylglutarate (Wang et al., 2023) (see Table 4) Table 4 Urine biomarkers in PD patients

This evolution reflects a series of pivotal discoveries, from its early identification as a mitogenic lipid to recent advances in receptor biology, enzymatic biosynthesis, and computational modeling (Fig