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The ob/ob and db/db mice exhibited an increase in intestinal permeability and significantly higher plasma endotoxin and proinflammatory cytokines such as IL-1 , IL-6, INF , and TNF- compared to wild-type mice
These strategies aim to expedite the development and manufacturing of complex therapeutic proteins, enabling faster delivery to patients in need
(2021) 321:G11G17
Comparative studies with other protective agents and investigation of combination therapies might reveal synergistic effects
[DOI] [PubMed] [Google Scholar] 73.Smith R.A.J., Hartley R.C., Cochem H.M., Murphy M.P
