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When fibrillin is mutated, such modulating function is missing and TGF- is overexpressed, thereby increasing the activation of its signaling pathway
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Evidences from mouse model of pancreatic cancer suggest that adipose browning precedes adipose tissue wasting (Kordes et al., 2021) and, consistently, expression of UCP1 and body temperature are both increased in pancreatic cancer patients before cachexia manifestation (Kordes et al., 2021)
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Mechanisms and treatment of dyslipidemia in diabetes
