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Sci Rep 13:20961

rhIGF-1/IGFBP3 autoantibodies were detected in 1 100 diluted plasma samples collected on day 19 using a porcine-specific ELISA kit (Genemed Synthesis, San Antonio, Texas)

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Given the complexity of mechanisms involved in drug resistance and survival pathways of tumor cells, combination strategies of GSH-conjugates with conventional chemotherapy or targeted drugs should provide very interesting perspectives for the treatment of drug resistant tumors

however, the strength of causal evidence varies across different resistance models.In BRAF inhibitor resistance, PHGDH knockdown reverses resistance, and exogenous serine supplementation rescues the resistant phenotype