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Dongre and Swami performed an open label study of pain response in patients with peripheral neuropathy who received oral sustained release pregabalin of doses of either 75 mg or 150 mg, which were given along with oral methylcobalamin 1500 g for a duration of two weeks ( n = 384)

They may need to rely on supplements or vitamin B12 injections to maintain adequate levels, and the frequency of supplementation will affect how long the vitamin stays in the body

Last reviewed: June 11, 2026 Last updated: June 11, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations