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The present review also integrates developments through early 2025, including the discontinuation of the pegtarviliase program and the rebranding of CDX-6512 as SYNT-202, with corresponding updates from clinical trial data, regulatory announcements and pipeline disclosures

Furthermore, our newly collected samples, which included 6 pairs of breast cancer tissues and adjacent normal tissues, further demonstrated that JAB1 was significantly overexpressed in breast cancer (Fig

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