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Low levels of 5-MTHF in the brain result in impaired transport of folates across the blood-brain barrier, which has been shown to result in cerebral folate deficiency (CFD)

How can you minimize these potential vitamin B12 side effects while maximizing the benefits

Cochrane Database of Systematic Reviews 2004, Issue 4

Because of the common mode of action in producing health effects, EPAs Reassessment assessed the cumulative toxicity of the compounds

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