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Sequeira JM, Desai A, Berrocal-Zaragoza MI, Murphy MM, Fernandez-Ballart JD, Quadros EV (2016) Exposure to folate receptor alpha antibodies during gestation and weaning leads to severe behavioral deficits in rats: a pilot study

In summary, CSF biomarkers show potential as effective outcome measures for clinical trials testing disease-modifying treatments for PD

[DOI] [PubMed] [Google Scholar] Verschaeve L, Leonard A

Biochem Pharmacol 41: 10991105

Clinical trial data indicates that most patients either adapt naturally or find relief through simple behavioral modifications within 4-8 weeks of consistent use
