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Res 184 , 106425 (2022)

Briefly, 10 l of serum was incubated with the top 12 abundant serum protein depletion kit (Thermo Scientific Pierce, Cat# 85164) and digested with trypsin on S-Trap column (ProtiFi, NY)

In terms of function, GGT plays a key role in maintaining cellular GSH levels

Effects of antihypertensive drugs on antioxidant enzyme activities and renal function in stroke-prone spontaneously hypertensive rats

378,379,380,381 Interestingly, a recent study suggested that RSL3 may induce cell death primarily through the inhibition of TRXR1 rather than the suppression of GPX4, highlighting the need for further studies to elucidate the precise mechanisms by which RSL3 triggers ferroptosis
