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This has positioned it as a subject of interest in neurobiological research, particularly in studies examining neuroprotective mechanisms and central nervous system signalling

One SOD3 form (termed the type C subunit) interacts tightly with heparin in the extracellular matrix (ECM), the other (termed the type A subunit) does not interact with the extracellular matrix

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Low BDNF in the hippocampus and amygdala is associated with increased anxiety-like behavior in animal models, and human studies show reduced serum BDNF in patients with generalized anxiety disorder

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