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These observations highlight the need for additional prospective studies to evaluate the nuances regarding MMR-D heterogeneity as well as markers of resistance to inform future trials of combination therapies to further improve outcomes for patients with EC

J Biol Chem 280: 3225432261 Pollard MG, Travers KJ, Weissman JS (1998) Ero1p: a novel and ubiquitous protein with an essential role in oxidative protein folding in the endoplasmic reticulum

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When food sits in the stomach longer and you lie down, the stomach contents are more likely to push back up into the esophagus

An increase in the activity of POD can remove excessive ROS and free radicals from plants, thus reducing the damage incurred by plant tissues in response to a stressful environment [25, 26]