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1 Introduction Male infertility represents a significant global health burden, contributing to nearly half of all infertility cases among couples (1)

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By improving dysbiosis, gut microbiota targeted intervention has shown promising outcomes in significantly reducing levels of these toxins in CKD patients, which, in turn, reduces the rate of occurrence of CKD-associated complications, and further studies that focus on this outcome are currently being explored

Statistical analysis All experiments were performed in at least triplicate and the results are expressed as the mean and standard deviation (SD)

ISBN 978-0-399-50764-9