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Description
It is abundant in human skeletal muscle, brain, and heart

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Dysfunctional SIRT3 causes the accumulation of long-chain acylcarnitines (LCAC)

Histological evaluation of testicular biopsies of azoospermic patients showed maturation arrest mostly at spermatid level

Caffeine and other methylxanthines also affect glomerular filtration, thereby influencing the elimination of drugs and their metabolites with urine
