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The areas attracting the most focused attention include inflammatory bowel disease, where the preclinical evidence base is deepest

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For instance, Nox-derived ROS play a role in cellular signaling related to the cardiovascular systems [22] and those in phagocytes (Nox2-derived) are involved in defense mechanisms of the immune system against foreign organisms [20]

doi: 10.1016/s0197-4580(99)00056-1
