glutathione s transferase a1 S-transferase and MRP1 form an integrated system involved in the storage and transport of dinitrosyl–dithiolato iron complexes in cells Frontiers | Glutathione S-Transferase Enzymes

Analogous with the majority of the previously reported oxidase-like nanozymes, pFeSAN as oxidase mimetics with oxygen as electron acceptor might generate reactive oxygen species (ROS, e.g.OH, 1 O 2 ,O 2 ) to oxidize TMB 1,2,3

B.ComasI.AebersoldR.et al

The role of iron in cancer Cancer initiation Iron plays a critical role in cancer initiation due to its ability to catalyze the formation of ROS, which induces oxidative damage to cellular DNA, resulting in mutations, genomic instability and promotion of malignant cell transformation [37, 38]

Fecal Analysis and Deworming Trial Since the majority of infectious causes of diarrhea resolve on their own or with supportive care, the following infectious agents are of most interest since they can cause life-threatening or ongoing (chronic) diarrhea

In other words, glutathione supplementation during good health primes the immune system for a robust response when it is confronted with a challenge