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Consider the following precautions: Avoid self-experimenting with large doses or stacking

[DOI] [PMC free article] [PubMed] [Google Scholar] 306.Zhang, H., Zhang, Y., Zhang, J

Moreover, given that dopamine agonist treatment in PD is limited by their intolerable side effects and diminished effectiveness over time, we selected astrocyte-specific PKM2 as a target to break this vicious cycle and found that pyridoxine can dimerize PKM2 to restore GSH levels, providing neuroprotection in the MPTP mouse model beyond targeting dopamine receptors