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Maximum Responder Rate (20%+ Loss) CagriSema 60% of CagriSema patients achieved at least 20% weight loss in REDEFINE 1, a higher responder rate than tirzepatide's across-trial data, though cross-trial comparison has limitations

Study Details Source Related Guidelines: Pharmacological Management of United States Adults with Overweight or Obesity The Obesity Society (TOS), Obesity Medicine Association (OMA), Obesity Action Coalition (OAC), March 2026 Management of Adult Overweight and Obesity Veterans Health Administration / Department of Defense (VA/DOD), November 2025 Sign up for alerts and stay informed on the latest published guidelines.

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Be sure to bring a complete list of medications and supplements to your consultation