glutathione for brain inflammation and neurodegenerative diseases: immunopharmacological implications Impaired Glutathione Synthesis in Neurodegeneration
Description
Downregulation or deficiency of pyruvate kinase leads to ATP depletion which in turn affects cell viability as well as accumulation of the glycolytic intermediates (2,3-diphosphoglycerate (2,3-DPG) that eventually leads to impaired glycolytic flux 46
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doi: 10.1021/acs.jafc.0c04789
While our cells thrive and benefit from some oxidation, bacteria, viruses, fungi, and cancer cells are damaged from oxidation
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& Gonzlez-Flecha, B
