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The predominant trigger for eNOS phosphorylation is fluid shear stress in the vasculature

Studies have shown reduced expression of both serine hydroxymethyltransferase and rhodanese in fibroblasts and lymphoblasts derived from FRDA patients [125]
[DOI] [PMC free article] [PubMed] [Google Scholar] 140.McQueen G., Lally J., Collier T., Zelaya F., Lythgoe D., Barker G.J., Stone J.M., McGuire P., MacCabe J.H., Egerton A

[51] showed that chondrocyte lipid peroxidation may contribute to cartilage aging and OA
