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We demonstrate in a humanised FcRn/albumin double transgenic mouse model (AlbuMus) the ability to tune half-life based on the albumin sequence fused with a BiTE-like bispecific (anti-EGFR nanobody x anti-CD3 scFv) light T-cell engager (LiTE) construct [(t 0.6 h (Fc-less LiTE), t 19 hours (Albu-LiTE-NB), t 26 hours (Albu-LiTE-WT), t 37 hours (Albu-LiTE-HB)]

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Effects on dopamine and serotonin systems address neurotransmitter dysregulation

The advantages described below will be realized and attained by means of the elements and combinations particularly pointed out in the appended claims

thus, these supplements are frequently given concurrently