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Several studies provide evidence that ROS, particularly O2 and H2O2, act as signaling molecules within cells (Franchina et al., 2018
C., Anderson, J., Paress, P
Additionally, iron chelating agents, including chloroiodohydroxyquine and its derivatives, as well as antioxidants, have shown efficacy in animal models of AD, though clinical trials are yet to be conducted (27,106,116)
Astolfi MCT
Thus, SEO1 which has for long remained a gene coding for an orphan transporter, has now finally a substrate and function assigned to it
