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In vitro functional analyses confirmed their mature hepatocyte characteristics: they showed high transcription and protein expression of ALB, A1AT, CYP3A4, and CYP2C9, comparable to primary human hepatocytes (PHs)

p-mTOR: phosphorylated mammalian target of rapamycin

Unlike broader-spectrum GHSs, ipamorelin targets the growth hormone secretagogue receptor (GHSR) with high specificity, with preclinical models showing minimal impact on ACTH or cortisol [peptidedosages.com]

Positive cells were sorted by GFP + (BD Aria)

Additionally, it is imperative to investigate whether the HT-induced ferroptosis via the Nrf2 pathway is modulated by other pathways