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Dopamine deficiency in the nigrostriatal pathway is one of the main causes of PD

In fact, about 90% of the total citrate in the body is stored in the bones and gets released into the blood when needed [138]

Malaviya AN, Sharma A, Agarwal D, Kapoor S, Garg S, Sawhney S (2010) Low-dose and high-dose methotrexate are two different drugs in practical terms
Three key elements are needed to trigger the ferroptotic pathway: 1) Polyunsaturated long-chain fatty acids (PUFAs) stored in phospholipid membranes 2) Redox-active iron 3) A defective lipid peroxide repair system
