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Opiates such as morphine reliably inhibit the behavioral, electrophysiological and biochemical responses evoked by acute thermal, mechanical and other noxious stimuli in rats

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Nle'-AngTV 100 pg/mL Serial dilutions of D-Nle-Tyr-Ile-NH-(CH 2 ) 5 -CONH 2 in 30% ethanol were prepared from the stock used to dose the animals for standard curves

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The trial also showed that the combination produced dose-dependent, sustained weight loss without concerning additional adverse effects the side effect profile was broadly consistent with what would be expected from each individual agent
