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Additionally, In the limited head-to-head trials available, ALC demonstrated comparable effectiveness to commonly used antidepressants, especially, Selective Serotonin Reuptake Inhibitor (SSRI), Serotonin-Norepinephrine Reuptake Inhibitor (SNRI), Tetracyclic Antidepressant (TeCA), Noradrenergic and Specific Serotonergic Antidepressant (NaSSA), Atypical Antipsychotics like Amisulpride used at low doses for antidepressant effects in this meta-analysis

doi: 10.2174/0929867311320100009 147 SzkudelskaKOkuliczMHertigISzkudelskiT

All treatments, including the control, were given using stomach tube gavage once daily for consecutive 56 days (8 weeks) to cover one complete spermatogenic cycle of the rat